Interruption of Escherichia coli Heat-stable Enterotoxin-induced guanylyl cyclease signaling and associated chloride current in human intestinal cells by 2-chloroadenosine Scott J Parkinson, Alexey E Alekseev, Luis A Gómez … [et.al]
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Diarrhea induced by Escherichia coli heat-stable enterotoxin (STa) is mediated by a receptor guanylyl cyclase cascade. The present study establishes that an intracellular nucleotide-dependent pathway disrupts toxin-induced cycle GMP (cGMP) production and
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