Systematic genetic study of Alzheimer disease in Latin America: Mutation frecuencies of the amyloid ß precuesor protein and presenilin in Colombia Diana Arango, Marc Cruts, Orlando Torres … [et.al]
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Nearly all mutations in the presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid ß precursor protein (APP) genes lead to early-onset Alzheimer disease (EOAD, onset age at or before 65 years). In order to assess the genetic contribution of these genes i
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